Garden prep-more advice needed


I'm planning to make a perennial garden in a disused dog run.  This
space has been vacant for three years now (no dog, just weeds). 
Planting will take place next spring.  
My question is:  What ammendments, if any, will be necessary because of
the earth having been used as a liquid waste receptacle for the dog?  I
already plan on compost, peat moss and mulch.  The area was a garden at
one time (before the dog joined the household).
Because this area is between the garage and the fence, can't be seen
from the house and doesn't get a lot of sun, I'm going to plant some
garden "thugs" and let them battle it out (and keep down the weeds).
Advice, comments, and suggestions will be welcome.
Thanks.
Betty (zone 8, coastal BC)

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