Re: status update 28Jan04

--- In SpaceAgeRobin@yahoogroups.com, "Neil A Mogensen" <neilm@c...> 
wrote:
> Walt,
> Thank you for telling of your background.  Sounds like you have 
just the kind of skills we need to help guide the SAGE process along.
While I have 2 years of grad work in genetics, the main thing I 
learned in grad school was to ask for help when I need it.  And who 
to ask for help.  I think those are the 2 most important things in 
life to know.

> On one occasion I happened to mention to the head of the Dept. that 
I wanted to see the full sequence from a DNA sequence to a visible 
characteristic and he said, "You are about five hundred years too 
soon."  If only he could see what is happening now.
Yes, my group in grad school was studying ways to make wider 
crosses.  We were using the drugs that stop, or reduce, rejection in 
organ transplants in humans.  The idea was that these same drugs 
might prevent rejection of pollen or growing hybrid embryoes.
And today, when my sister-in-law had a kidney transplant, not one of 
the drugs we used back 25+ years ago is commonly used.
And the idea of just taking a gene from one species and putting it in 
another was just science fiction.  
Only 6 or 7 years later, I went back and audited the course on gene 
splicing.

> 
> Glad you are with us, Walt.  Please don't hesitate to make 
suggestions, agree or disagree with anything said, especially from my 
ramblings.  Often I speak from imagination fed by ignorance.  I don't 
take being set straight with anything other than gratitude.
> 
> 
Actually I have been impressed with the plans.  I have spoken up a 
couple of times in passing.  What I had to say wasn't terribly 
different from what was being said.
I did say that if anyone was making crosses of SA iris with pumilas 
or arils, they should keep track of how many of what they get, and 
not just discard the poor ones without counting and recording them.
This isn't to replace the SAGE program, but any information we can 
aquire on the segregation at a diploid level might be a useful clue 
on how to interpret the results at the tetraploid level.
And one thing that needs work, and others have said this, is to 
figure out what environment is best for expressing the traits.  
Things have been mentioned.  More needs to be brought together on 
this.
There will be a problem interpreting the data at first at least, 
because we won't know if a given variety has how many doses of the 
gene(s).  But you (we) are on the right track.
Walter



 

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